There are a few common practices for configuring when backups occur. The most common option is on a fixed schedule, such as once a day, week, or month. The second, which we prefer, is to upload file changes whenever they're changed and saved, otherwise known as a continuous backup setting. Services only transfer the modified part of the file in this scenario, so as not to overburden your internet connection or take up unnecessary storage. A third way is simply to upload files manually. Some may appreciate this degree of control, but this method is only effective if you remember to regularly run the backup.
Many services also offer a feature called versioning. This saves incremental changes you make to files as recoverable snapshots of the file. It's useful in case you need to get back information from an earlier version or if your latest file save becomes corrupted. Services vary widely in how many versions they keep and how long they're saved. Best-in-class services, such as SOS Online Backup and SpiderOak ONE keep an unlimited number of file versions forever.